Job Description

Clinical Research RN

Cancer care is all we do

Hope in healing

Cancer Treatment Centers of America® (CTCA), part of City of Hope, takes a unique and integrative approach to cancer care. Our patient-centered care model is founded on a commitment to personalized medicine, tailoring a combination of treatments to the needs of each individual patient. At the same time, we support patients’ quality of life by offering therapies designed to help them manage the side effects of treatment, addressing their physical, spiritual and emotional needs, so they are better able to stay on their treatment regimens and get back to life. At the core of our whole-person approach is what we call the Mother Standard® of care, so named because it requires that we treat our patients, and one another, like we would want our loved ones to be treated. This innovative approach has earned our hospitals a Best Place to Work distinction and numerous accreditations. Each of us has a stake in the successful outcomes of every patient we treat.

Job Description:

Under direct supervision of the Clinical Research Manager the incumbent will coordinate phase I through III oncology research studies and be responsible for maintaining and assuring protocol compliance for all research subjects. The Clinical Research Nurse (CRN) is responsible for regulatory and compliance documentation including protocol training for the clinic staff, imaging department and infusion center, test article accountability, and IRB transactions. The CRN is responsible for establishing relationships with outside providers for required tests not available in-house.

The CRN must demonstrate an in-depth knowledge of applicable federal regulations, institutional guidance documents and SOPs for the conduct of clinical trials to ensure human subject protection, compliance with protocol and regulatory requirements and the thorough collection, recording and maintenance of data and source documentation.

The CRN collaborates with Investigators in review of potential protocols and in research subjects’ recruitment and pre-screening for protocol eligibility. The CRN is responsible for developing an individualized strategy for identifying potentially eligible patients for each study. The CRN presents trial concepts and details to the research subjects, participates in the informed consent process, enrolls and coordinates care of subjects in compliance with protocol requirements. The CRN may provide teaching on investigational agents/devices to research subjects and maintains test article accountability. In collaboration with Investigators, the CRN monitors subjects for changes in condition, adverse events, concomitant medication use, protocol compliance, response/reactions to test articles, and thoroughly documents all findings. The CRN is responsible for accurate and timely data collection, documentation, and reporting. The CRN is responsible for entering all patient data in CTMS.

The CRN schedules and/or participates in off-site investigator meetings, pre-site selection visits, site initiation visits, site-assessments, monitoring visits, and auditing activities as delegated by the Research Manager. The CRN may be responsible for and/or assist with completion and maintenance of regulatory documents in accordance with regulations, hospital and organizational policies and Standard Work Instructions. The CRN will participate in required training and education programs, provide clinical research education to local clinic staff, and ensure site research quality by practicing in compliance with policies, SWIs, principles of Good Clinical Practice (GCP) and applicable federal, state, and local regulations. The CRN may develop or assist with development of study tools including source documents and eligibility checklists and criteria cards and may be involved in the collection, processing, and shipping of protocol required lab specimens. The CRN maintains adequate supplies to conduct the studies and orders replacements as needed. The CRN maintains the equipment inventory (per protocol) and has appropriate certifications as required by protocol activities e.g., IATA certification. The CRN assists clinicians (LPNs, MAs, and/or RNs) as needed to ensure that protocol required specimen collections, electrocardiograms, vital signs, study drugs and customary usual care medications, IV start and IV discontinuation as well as follow-up observations are performed per protocol (as applicable).

The Clinical Research Nurse will provide consistent oversight to ensure competent and standardized practices, and coordinate strategies to enhance departmental communication and collaboration.


Skills, Education and Additional Information

Experience Required:

  • Minimum 2 years clinical research experience
  • Bachelor's Degree in nursing (BSN)
  • Valid RN license
  • Basic life Support (BLS) within 1 month of employment
  • Human Subjects Protection (HSP) within 1 month of employment
  • Good Clinical Practice (GCP) within 1 month of employment
  • International Air Transport Association (IATA) within 1 month of employment
  • Certification through SoCRA, ACRP, or other reputable entity within 3 years
  • Basic oncology class within 3 months of employment

Preferred Experience:

  • Minimum 3+ years of experience
  • Minimum 3+ years of oncology experience
  • Research Certification through Society of Clinical Research Associates, Association of Clinical Research Professionals, or other reputable entity
  • Phase I clinical trial experience

Pay Range

$64,411.78 - $106,120.56

Placement within the identified pay range is based on individual and market factors including, but not limited to, experience, education, credentials (including licenses and certifications), geographic location, market competition, skill set (including market availability of required skills), assigned/anticipated job tasks, and level of responsibility.  These factors are considered without regard to an individual’s status as a member of any protect group pursuant to federal, state, and/or local law.

We win together

Each CTCA employee is a Stakeholder, driven to make a true difference and help win the fight against cancer. Each day is a challenge, but this unique experience comes with rewards that you may never have thought possible. To ensure each team member brings his or her best self, we offer exceptional support and immersive training to encourage your personal and professional growth. If you’re ready to be part of something bigger and work with a passionate, dynamic group of care professionals, we invite you to join us. 

Visit: to begin your journey.

Application Instructions

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